Myelofibrosis blood manifestations include normocytic normochromic anemia, white blood cell counts may be increased or normal, and teardrop red blood cells may be found.
1. Myelofibrosis is a diffuse fibrous tissue proliferation of the bone marrow, the cause of which is not yet clear. Blood tests show that most patients will have normocytic normochromic anemia, and a small number of naïve red blood cells can be seen in the peripheral blood, while mature red blood cells are of different shapes and sizes. If teardrop-shaped red blood cells are found, it is of diagnostic value.
2. The number of leukocytes may be increased or normal, with mature neutrophils predominating, alkaline phosphatase activity may be elevated, and sometimes naïve granulocytes may be seen.
3. Platelet counts vary, and in most cases are elevated, but their function is often defective.
The presence of myelofibrosis requires active consultation and rational treatment as prescribed by the doctor.