Cranial repair surgery is no longer a difficult task in modern medicine; it is a routine procedure. Although the surgery is minor, the patient’s choice of material is extremely critical, and today there are traditional titanium mesh materials and more advanced PEEK materials on the market. Although titanium mesh is widely used, its results are less than ideal, and some patients have reported sensitivity to hot and cold reactions after surgery, chronic local pain, more subcutaneous fluid, and a host of other problems, which leads to the need for review or a second surgery, bringing greater trauma to the patient. If titanium mesh is not used, will the PEEK material suffer from the same condition? The answer is no. The PEEK material is scanned through the patient’s skull by CT and shaped by 3D reconstruction to create a repair material that matches the size and shape of the cranial defect area and is surgically fixed to the patient’s defective skull, providing effective mechanical protection of brain tissue. The PEEK cranial repair perfectly compensates for the disadvantages of titanium mesh, which is strong but flexible, with a weight and texture very close to human bone, and will not dent or deform even when subjected to impact.