Edema in nephritis patients may be related to abnormal hormone secretion, decreased filtration function, increased systemic capillary permeability, hypoproteinemia and other reasons.
1. Abnormal hormone secretion: patients with nephritis may have hormone secretion disorders, such as decreased secretion of antidiuretic hormone, inhibition of renin-angiotensin-aldosterone and other activities, which leads to increased secondary aldosterone, aggravating sodium retention and symptoms of edema.
2. Decrease in filtration function: when patients with nephritis suffer from renal insufficiency and decrease in glomerular filtration rate, it will lead to decrease in water excretion and sodium retention.
3. Increase in systemic capillary permeability: fluid can easily enter into the tissue space from the blood vessels, which leads to edema and other conditions.
4. Hypoproteinemia: the decrease of plasma protein level, especially the decrease of albumin level, causes the decrease of plasma colloid osmotic pressure, and the water can easily move to the tissue interstitial space.
It is recommended that patients with nephritis and edema should go to regular hospitals in time for medical checkups and standardized treatments as prescribed by doctors.