The steps of liver abscess puncture include preoperative abscess localization, deciding the puncture access according to the abscess localization, and placing tubes for drainage. Liver abscess can be identified by preoperative liver ultrasound, abdominal CT and other auxiliary examinations to clarify the location, size and depth of the abscess, and accordingly determine the body puncture approach. After determining the puncture site, local infiltration anesthesia is usually performed around the puncture site, and the puncture needle is inserted along the puncture point after sufficient anesthesia, and the pus is pumped out, which means that the puncture is successful, and the abscess drainage tube is left in place, and the tube can be fixed. The drainage tube can be removed when the drainage flow gradually decreases and the abscess cavity is closed by liver ultrasonography or abdominal CT examination. Liver abscess puncture is an important means of treating liver abscess, and positive cooperation with the treatment can often lead to a better prognosis. If there is any maladaptation, treat it as soon as possible to avoid progression of the disease and adverse consequences.