High urine microalbumin is not necessarily a kidney disease, but may also be related to other factors such as strenuous exercise and urinary tract infection. Urine microalbumin is normally less than 30mg/L, which is an indicator for early diagnosis of glomerulopathy. When urine microalbumin is high, it may be caused by kidney diseases such as diabetic nephropathy, hypertensive nephropathy, lupus nephropathy, etc., but it may also be related to other factors such as strenuous exercise, urinary tract infection, etc., so it is not necessarily caused by kidney disease. In addition to the above factors, some patients with high urinary microalbumin also need to be alert to hemolytic anemia, leukemia, crush syndrome, taking drugs that have an impact on renal function and other factors, attention should be paid to differential diagnosis. It is recommended that patients with high urinary microalbumin consult a regular hospital in a timely manner, follow the doctor’s instructions to further improve the relevant examinations, to clarify the cause of the disease, and standardized treatment.