Allergy to chemotherapy for breast cancer is a relatively common clinical toxic side reaction, and drug allergy has more common and milder manifestations as well as more severe manifestations. The more common manifestations include rash, itching, fever, etc., which only need routine symptomatic treatment. More severe allergies require immediate discontinuation of the medication, anti-allergy treatment with dexamethasone, or symptomatic treatment with diphenhydramine and oxygenation. The most serious allergy is anaphylaxis, which is a life-threatening allergic reaction. Rescue for anaphylaxis has the following main aspects: 1, timely discontinuation of chemotherapeutic drugs, to be able to ensure that the amount of allergens entering the body is minimized; 2, close observation of the patient’s vital signs, such as changes in blood pressure, blood oxygen; 3, immediate subcutaneous or intramuscular injection of epinephrine; 4, administration of dexamethasone, ipratropium or respiratory stimulants.