Esophageal cancer, or esophageal cancer, is a malignant tumor that originates in the esophagus and is most common in middle-aged and elderly men. If esophageal cancer is not treated in the middle and late stages or if the treatment is not effective, more than 90% of patients will survive for about 1 year. If the treatment effect is good, the survival period of patients will be prolonged. The common symptom of middle and late stage esophageal cancer is progressive dysphagia, and in severe cases, there may be food reflux and vomiting. When esophageal cancer infiltrates and compresses different neighboring tissues and organs around, it will also produce different accompanying symptoms, such as hoarseness, cough, eructation, jaundice, pneumonia, etc. When the tumor invades the aorta it can cause lethal hemorrhage and may not survive for 1 year without any treatment or with poor treatment. Patients with advanced stage are in cachexia state and the survival time will be even shorter. Surgery, such as esophagectomy and reconstruction, can be adopted in the middle and late stages of esophageal cancer. Surgery to remove the lesion and reconstruct the function, combined with chemotherapy and radiotherapy, can improve the survival quality of patients. However, because most patients are already in the middle and late stages at the time of diagnosis, even if the surgical resection rate is improved, the long-term outcome is still not satisfactory, and only about half of the patients can live up to 5 years. For patients with upper segment esophageal cancer and those with contraindications to surgery, preoperative or postoperative radiotherapy can also be used to extend the survival period. The daily care of patients with mid-to-late stage esophageal cancer plays an important role in survival and prognosis. Patients should have regular follow-up examinations, ensure good rest and rest habits, and eat mainly liquid diet on a daily basis. In addition, the amount of salt and protein intake in the diet can be increased appropriately to avoid insufficient nutrition and water-electrolyte intake.