Painful pressure on the outside of the nose, this condition is mainly seen in the following diseases: 1. The patient has local dryness of the nasal mucosa, local erosion and ulceration of the mucosa. So in this case, if you press on the nose, the nose will have a painful sensation. For this case then you can do nasal endoscopy. If the examination is clear, you can use compound menthol nasal drops, and recombinant bovine basic fibroblast growth factor gel, to apply the nasal cavity can be, after 7-15 days can be good; 2, some patients have nasal dysentery infection, nasal dysentery is a bacterial infection under the mucous membrane of the nose, some patients if dysentery infection, pressure on the outside of the nose will have a painful sensation. This kind of patients have very clear localized congestion in the nose, the local may be swollen and painful to press, carry out penicillin anti-inflammatory treatment on it; 3, some patients have long tumors in the nasal cavity, when doing local pressure, it may cause local pain and discomfort, this situation is recommended to do nasal endoscopy, and at the same time perfect sinus CT examination on it.