Acute urticaria preferred sedative effect of the second generation of H₁ receptor antagonist treatment, such as cetirizine tablets, ebastine tablets, etc., the specific use of drugs need to comply with medical advice. 1. Cetirizine: common dosage forms are capsules, tablets and oral solution, clinically used in the treatment of seasonal or perennial allergic rhinitis and urticaria. It is forbidden to use for those who are allergic to this product, severe renal impairment, pregnant and lactating women, and headache, dry mouth, itchy skin, diarrhea and other adverse reactions may occur after taking it. 2. Ebastine Tablets: It is a systemic antihistamine used for the treatment of urticaria, allergic rhinitis, eczema and itchy skin. It is prohibited for those who are allergic to this product, pregnant women and lactating women, etc. Rash, swelling, rash, swelling, headache and other adverse reactions may occur after taking the drug. The appearance of acute urticaria should go to the hospital in a timely manner, under the guidance of the doctor to choose the drug, to avoid blind use of drugs to cause adverse consequences.