Cranial bone repair surgery is a common surgical procedure, and the cost of repair surgery is related to the cost of examination, hospitalization, materials and surgery. The purpose of the surgery is to take repair materials to make a good repair to the defective area. Titanium mesh is currently used as the most common cranial repair material, its price is not high, but there are great defects and poor postoperative results, so cranial repair also needs to choose more advanced repair materials. With the progress of modern technology, polyetheretherketone peek material has become the ideal choice for skull repair surgery, although the price of this material is a little more expensive, but the effect is very superior. At present, very few hospitals in China use polyetheretherketone peek cranial repair material as a cranial repair implant material, while introducing the concept of plastic surgery, based on 3D printing, for different patients to develop personalized peek cranial repair plastic surgery program, in reducing postoperative complications at the same time, to achieve the appearance of repair plastic beauty. PEEK repair material, although high in price, is based on the characteristics of high-performance molecular materials. peek’s clinical results are unmatched by other materials. It can be highly compatible with autologous cranial bone and is comparable to autologous cranial bone in terms of elasticity, heat transfer, stiffness, and stability, especially for pediatric patients, who are better able to adapt to the growth and development of autologous cranial bone. Although the PEEK material was chosen as a replacement for the cranial bone, it can save many patients from the painful aftereffects.