The starting dosage of 3 ml of simethicone is 0.25 mg per week, which should be increased to 0.5 mg once weekly after four weeks and may be increased to more than 1 mg per week after at least four weeks.Doses of more than 1 mg per week are not recommended and are subject to physician’s instructions. 3 ml of simethicone is indicated for the treatment of type 2 diabetes mellitus at a dosage starting at 0.25 mg subcutaneously once a week, which should be increased to 0.5 mg once a week after four weeks, and may be increased to more than 1 mg per week after at least four weeks depending on the condition of the patient. weekly doses in excess of 1 mg per week are not recommended, specific dosages and adjustments to the regimen should be made under the direction of a physician. The drug may cause nausea, diarrhea, vomiting, hypoglycemia, fatigue, amylase elevation and other adverse reactions, and is contraindicated in allergy, medullary thyroid carcinoma patients, pregnant women, lactating women and so on. The drug should be used under the guidance of professional physicians, and should not be used on its own. If any adverse reaction occurs after the use of the drug, it is necessary to stop the drug in time and consult a doctor.