There are many causes of perianal redness with itching. First of all, the cause should be analyzed to keep the area around the anus clean and reduce local irritation. If the itching around the anus is severe, some medications can be applied, such as oral antihistamines like Benadryl or paracetamol. If the itching around the anus is more severe and the symptoms are more serious, intravenous injection of 10% calcium gluconate can also be given. Keeping the perianal area clean, you can apply drugs for fumigation, a common drug is anti-itch soup, the main ingredients are bitter ginseng, serpentine, Sichuan pepper, cypress with water for perianal fumigation first and then wash, can play a role in the treatment of itching.