The ovarian function of women in their 40s is gradually declining, the ability to conceive is further reduced, and the risk of fetal malformations is relatively higher, so it is important to pay attention to supplementing folic acid and a variety of nutrients when preparing for pregnancy. Folic acid deficiency may lead to fetal neural tube malformations and fetal growth retardation. The demand for folic acid during pregnancy is greater than during non-pregnancy, so it is best to start supplementing folic acid at 0.4mg per day three months before conception, while paying attention to the combination of other nutrients and eating more fresh vegetables and fruits. Multi-nutrients include zinc, iron, calcium, multi-vitamins such as vitamin A, B1, B6, B12, C, D, etc. You can eat lean meat, beef and lamb, liver, animal blood, walnuts, peanuts, dairy products, fish, eggs, and a variety of fresh vegetables and fruits as appropriate. At the same time, 3 months before pregnancy can also take some nutritional preparations, such as multivitamin tablets, can be supplemented with a variety of vitamins and some trace elements.