Cranial defects are extremely harmful to human body, if not timely repair surgery, may lead to cranial dizziness, headache, and other manifestations of the patient, and even irritability, fear of noise, psychological shadow. Therefore, once the skull is damaged, cranial bone repair surgery should be done as early as possible when conditions permit. Cranial bone repair surgery is a routine surgery of brain neurosurgery, with mature technology and clinical success cases abound. What is worth considering is the choice of repair material. The traditional titanium mesh material is prone to large postoperative hot and cold reactions, with external temperature stimulation, patients are experiencing chronic symptoms such as headaches, and postoperative infections are also more common. So much so that most patients will undergo a second surgery. The ideal material for cranial bone repair is PEEK, a newly developed polymer biomaterial that has been in clinical use for a shorter period of time than titanium mesh, but is many times more effective than titanium mesh. PEEK has the property of being highly adaptable to autogenous cranial bone, and doctors can use three-dimensional reconstruction technology to perfectly recreate the damaged bone window, with a size and shape that is unrecognizable from the previous site. The PEEK material, which highly reproduces the physiological structure of the skull, is very popular among patients because it is comparable to the autologous skull in terms of organization, hardness, stability, and thermal insulation. In the strength of the regular specialized hospitals, except for the skull damage is particularly serious, in the experienced doctor under the knife, the general repair surgery can be completed in one hour. Moreover, there is no rejection reaction and the risk of surgery is small. According to a large number of clinical facts have also confirmed this, patients who have received skull repair surgery, has not yet found a case of post-operative complications. Warm reminder: through the above understanding of the skull repair surgery, it is recommended that patients go to the regular hospital as soon as possible to take the appropriate materials to repair the skull, early repair, early recovery.