Decreased vision with some yellow pupils can be seen in vitamin deficiencies, liver and gallbladder diseases, pancreatic cancer, etc., and should consult a doctor in time to clarify the cause of the disease. Vitamin A deficiency, due to retinal violet synthesis obstacles, manifested as a decline in dark adaptation, blurred vision, photophobia, conjunctivitis, conjunctival yellowing, but also can be manifested as anemia, skin roughness. Hepatobiliary diseases such as gallbladder stones, cirrhosis, hepatitis B, etc., due to liver synthesis and catabolic metabolism disorders, bile excretion disorders caused by bile duct obstruction, manifested as yellowing of skin and decreased vision. Pancreatic cancer mainly causes obstructive jaundice, manifested by yellowing of skin or sclera, itching of skin, and decreased vision. Vision loss pupil some yellow is not a normal manifestation, should promptly seek medical attention, clear cause of the disease after active treatment.