Taking berberine hydrochloride may have an effect on the results of some medical examinations, such as carbon 14 breath test, generally most of the results of medical examinations are not affected. The main function of berberine hydrochloride is anti-inflammatory and anti-bacterial, preventing and controlling infections, and it is generally used to treat infectious diseases of gastrointestinal tract, such as bacterial dysentery and gastroenteritis, and in addition, it can also treat Helicobacter pylori. Therefore, when berberine hydrochloride is used to treat Helicobacter pylori, if the carbon 14 breath test is performed without stopping the medication, the result may be affected. Berberine hydrochloride itself has fewer side effects and fewer oral adverse reactions. However, there are occasional adverse reactions such as nausea, vomiting and skin rash, which usually disappear gradually after stopping the drug. The medication should be administered under the guidance of a doctor, and it is recommended not to take the drug orally by oneself. In addition, if there is any related disease, it is recommended to go to the hospital for clarification of the cause and symptomatic treatment under the guidance of a doctor.