When you have your period while taking estradiol valerate tablets, stop using the medicine. This is because the medication is an estrogen, and if you take it again it will result in a significant decrease in menstrual flow, so you should stop using the medication. The vast majority of this drug is taken on the 5th day of menstruation, and is taken for 21 consecutive days before stopping, and menstruation will occur 3-7 days after stopping, and the vast majority of them will not experience menstruation during the period of using the drug. If this happens, it is recommended to consult a doctor at the hospital in time. In addition, find out whether you are taking the medication as prescribed and whether the dosage is up to the therapeutic dosage, and then decide next month whether you need to continue with the medication.