The redness and broken skin at the base of the thighs of infants is often due to diaper rash, which is mainly related to local friction and irritation, and some infants’ diaper rash can be secondary to bacterial or fungal infections. You need to keep the skin dry and use some topical medications to treat it. 1. Keep the local skin dry: parents need to take good care of the baby, change the diaper frequently to prevent skin irritation; keep the baby’s skin clean and dry, especially the skin in the area of frequent contact with the diaper; the baby’s buttocks and thighs should be exposed to the air for a period of time every day, which is conducive to the recovery; dress the baby in appropriate diapers or diapers, such as highly absorbent diapers. 2. Topical medication: zinc oxide cream can reduce inflammation, moisturize the skin, protect wounds and promote dry skin. If the local broken skin is accompanied by redness, swelling and oozing, erythromycin ointment can be applied to prevent infection. If secondary fungal infection can be used externally ketoconazole ointment. The specific use of drugs need to be diagnosed by a doctor, follow the doctor’s instructions to use, do not self-abuse.