Migraine is a common disease in neurosurgery, and many patients and doctors say that this stubborn headache disease is difficult to treat, and it often recurs due to excessive fatigue, irregular diet and emotional stress. The attack of this disease not only makes the patient’s body suffer great pain, but also causes indelible damage and impact on the patient’s psychology and spirit in the long run. As we all know, only when we understand the root cause of any disease can we take targeted treatment measures. However, modern medicine does not have a definite method for the pathogenesis and triggering factors of migraine, and there are mainly vascular theory, neurological theory and trigeminal vascular theory before, but none of these doctrines can explain the pathogenesis of migraine very clearly. Therefore, the treatment of migraine in many local hospitals only adopts traditional methods such as acupuncture, massage and medicine, and the treatment effect is not satisfactory. In recent years, medical research has confirmed that the blood vessels and nerves of most migraine patients are crossed, entangled and adhered, and along with the jamming of the blood vessels, the pain-causing transmitters in the blood gradually stimulate the nerves with the pulsation of the blood vessels under the triggering of external conditions, resulting in the release of pain from the nerves and making the patients suffer. Based on this theoretical etiology, Yang Tao, the neurosurgeon of Zhengzhou Yellow River Central Hospital, innovatively introduced microvascular decompression surgery, using a minimally invasive surgical method to precisely find the site of the lesion under the display of a high-powered microscope, safely isolate the blood vessels and nerves through fine operation, and protect the nerves with special materials to prevent the nerves from being compressed again, easily curing migraine for patients. Some patients ask, “Is it better to treat migraine with surgery or with closed-loop treatment? The closed injection can only provide a certain amount of relief for a short period of time, and the condition will come back again a few weeks to a month after treatment, so closed treatment for migraine is only a short period of relief. Therefore, we remind all migraine patients that if they want to get rid of migraine, they need to go to the hospital for detailed examination, and if the migraine is caused by the compression of nerves by blood vessels, they can be treated by microvascular decompression and regain recovery.