A high pressure of 105mmHg and a low pressure of 54mmHg is usually not normal. Because the standard blood pressure is 120/80mmHg, the minimum range of low pressure is 60/80mmHg, low pressure is already below the minimum standard, so it is not normal. High pressure 105mmHg low pressure 54mmHg in general may be due to physiological reasons or pathological reasons, if the long-term blood pressure is lower than the normal standard, and there is an adverse reaction is likely to be due to pathological reasons, if the blood pressure is lower than the normal standard and does not have any adverse reaction, it may be due to emotional fluctuations or irregularities in life resulting in physiological hypotension, this situation generally does not require special treatment, only the low pressure is below the minimum standard, so it is not normal. This situation generally does not require special treatment, just need to adjust the mood or regular life can be. If the high pressure is 105mmHg and the low pressure is 54mmHg, and there is an adverse reaction, you should go to the hospital immediately for examination, combined with the actual situation, under the guidance of the doctor to take reasonable treatment, and do not blindly use medication, so as not to avoid misunderstanding the disease.