How do diseases arise? “Su Wen ~ meridians and veins,” put forward: “so spring, fall, winter and summer, the four seasons of yin and yang, sick from the overuse” of the morbidity concept. Why? Because the human organs, meridians, blood, yin and yang, in the adaptation of spring, summer, autumn and winter, the four seasons, day and night, happiness, anger, sadness and joy, food and labor changes in nature and personnel, there is a range of self-regulation, the potential for self-regulation is extremely strong, cold, hot, greed for darkness, stay up all night, think that there is no big deal of harm. But in fact, the disease is so little accumulated, if the body can regulate and bear the scope, the internal organs will malfunction and produce disease.