Incontinence in acromegaly is caused by damage to the nerves and muscles that control bowel movements, and it is usually difficult to return to normal, and care needs to be taken to avoid depression and mood swings. Amyotrophic lateral sclerosis is a disease caused by damage to motor neurons. When the nerves that innervate the anal sphincter and urethral ring muscles are damaged, these muscles will relax and become unable to control urination and defecation on their own, resulting in incontinence. Since acromegaly is currently an irreversible disease, once acromegaly incontinence occurs, most of them can not be restored to the normal level, but can be slowed down by rehabilitation training to improve the development of the disease and improve the ability to live. For patients with incontinence of urine and faeces, they must be patient during the rehabilitation training process, and can be provided with a special potty chair to assist them to go to the toilet. During the period of assisting the patient to go to the toilet, attention should be paid to maintain the patient’s balance to prevent falls. Since patients with acromegaly cannot leave the care of their families, attention must be paid to the patient’s mood in the process of accompanying and caring for the patient to avoid the occurrence of depressive episodes affecting the patient’s quality of life.