Brown blood with leuprolide acetate for IVF transplantation is usually normal, and active care is recommended. One of the common adverse reactions to leuprolide acetate is that it can cause uterine bleeding, so this condition is generally considered to be a drug-induced adverse reaction, and the symptoms are usually mild and do not require special treatment. Before a woman undergoes IVF transplantation, she is usually required to receive subcutaneous injections of leuprolide acetate, a condition known as a down-regulation injection, which is designed to regulate the secretory function of the pituitary gland, avoid spontaneous ovulation, and strive for more synchronized development of high-quality follicles. Common adverse reactions to leuprolide acetate include nausea, vomiting, abdominal pain, diarrhea, and constipation. It is also contraindicated in patients with prostate cancer and uterine fibroids. Leuprolide acetate is associated with certain risks and should be used under the supervision of a physician.