Female 58 years old left calf belly soreness may be over-exercise, lumbar spine lesions, thrombophlebitis, etc., should be taken according to the cause of the general treatment, medication, physiotherapy or surgical treatment. 1. Excessive exercise: may be due to the body’s usual lack of exercise, the recent sudden strenuous exercise caused by normal physiological phenomena, pay attention to rest, hot compresses, generally can relieve the symptoms. 2. Lumbar spine lesions: most commonly seen in lumbar disc herniation, spinal stenosis, etc., caused by nerve root compression, lumbar traction, oral non-steroidal drugs such as ibuprofen, etc. to relieve the pain, the symptoms of serious cases may require surgical treatment. 3. Thrombophlebitis: mainly caused by thrombosis in the venous lumen, usually pay attention to elevate the affected limbs, avoid sitting and standing for a long time, and take non-steroidal anti-inflammatory drugs such as ibuprofen and acetaminophen to alleviate the pain symptoms. Serious cases need to take intervention. If the left calf soreness symptoms continue to fail to improve, it is recommended that the patient consult a doctor in a timely manner to clarify the cause of the targeted treatment, do not blindly use drugs.