If the cause of the headache cannot be identified, most headaches are considered to be primary. Migraine, tension headache and cluster headache are the most common clinical causes. Tension headache occurs mostly in young adults and is mainly characterized by persistent swelling, aching, and dull pain at the top of the head, the back of the head, or bilateral frontotemporal areas. Some patients may experience a sensation that they are about to explode, or they may get worse in bursts. The main treatment is symptomatic pain relief, and commonly used medications include ibuprofen, indomethacin and naproxen, and acetaminophen may also be applied. Migraine is characterized by recurrent one-sided throbbing headache, which may be followed by nausea and vomiting. A few typical patients may have aura of visual, sensory or motor dysfunction before the onset. Mainly, headache attacks can be treated with symptomatic pain relief, which can be applied with ibuprofen, indomethacin and neproxen. Ergotamine caffeine, zolmitriptan and sumatriptan can also be applied if the headache is severe. If cluster headache is considered, the headache is usually severe, and most of the headache is on one side of the orbit, around the eye, and may also appear in the frontal or temporal area.4. The headache is usually a drilling pain, pulling and tearing pain or pins and needles pain, and the headache may be accompanied by conjunctival congestion, nasal congestion and lacrimation, and is mainly treated with zolmitriptan and sumatriptan.