Children enema may have led to intestinal flora dysbiosis, organ function damage or intestinal bleeding and other hazards, but generally after standardized operation will not have serious harm. 1. Intestinal flora dysbiosis: enema is mainly a certain enema solution from the anus through the rectum into the colon, so as to play the role of defecation, intestinal cleansing, etc., but it may be the intestinal discharge of beneficial bacteria, destroying the intestinal flora, resulting in bacterial flora dysbiosis. 2. Damage to organ function: enema irritation is relatively large, and drug absorption is also relatively rapid, if improper operation, it may lead to adverse drug reactions, and even cause liver and kidney function damage. 3. Intestinal bleeding: in the process of enema, it may cause damage to the intestinal mucosa, resulting in intestinal bleeding. Children’s enema treatment must be operated by professionals, and after the enema, pay attention to observe whether there are uncomfortable symptoms, in order to consult the doctor in time.