Brain tumor refers to tumors and brain metastases originated from intracranial tissues, which can manifest as increased intracranial pressure and various neurological symptoms. Craniotomy is the main treatment method for brain tumor, and the specific steps are as follows. Craniotomy for brain tumor needs to clarify the specific location and size of the brain tumor first, and choose the appropriate surgical incision according to the specific growth location of the tumor. The surgical process starts with anesthesia injection, then the hair is removed cleanly, the scalp is cut open to fully expose the location of the skull, and special equipment is used to cut open the local skull. If the tumor is superficial, the tumor itself can be seen after opening the skull, and the tumor can be removed gradually with the help of a microscope. If the location of the tumor is deeper, it is necessary to pull open the brain tissue to find the location of the tumor, and then with the help of a microscope, separate the tumor from the surrounding blood vessels and nerves and brain tissue, and then gradually carry out the resection of the tumor, and then close the cranial cavity and suture the wound. After the operation, patients should pay attention to local care, keep the wound hygiene and clean to prevent secondary infection. It is recommended that patients choose regular hospitals for brain tumor treatment.