Symptoms of pancreatic cancer in late stage include epigastric pain, digestive symptoms, jaundice, abdominal mass and so on, details are as follows: First, epigastric pain: the pain is located in the left upper abdomen or umbilicus, and it is persistent, and there is lumbar and back pain as well as abdominal pain is intense, which affects the sleep and diet, and it is often to take knee and elbow position to seek for relief, and the pain is because of the cancer encroaching upon the retroperitoneal nerves. Digestive symptoms: vomiting, vomiting blood and black stool may occur in late stage, which is mainly caused by tumor infiltration and compression of stomach and duodenum. Jaundice: 80% of pancreatic cancer patients will have progressive aggravation of jaundice, especially pancreatic head cancer patients, at this time, there will be red tea-colored urine, clay-colored stool and obvious itching of skin. Abdominal mass: patients with advanced stage can touch abdominal mass, which is irregular in shape, of different sizes, hard and fixed, and may be accompanied by pressure pain. Wasting and fatigue: related to long-term consumption, reduced diet, indigestion, etc., patients will experience wasting and fatigue, accompanied by anemia, low protein and other malnutrition symptoms.