There are many patients who find frequent toothache, and when they are examined, they are finally diagnosed with trigeminal nerve pain, so how can we better identify the characteristics of the disease? How can toothache and trigeminal neuralgia be identified? It is important to draw attention to this. Many people mistakenly think of toothache as a common toothache, and do not go to treatment in time, but keep on pulling teeth, and then only after a long time was it diagnosed as trigeminal neuralgia. Trigeminal neuralgia is a very common disease in neurosurgery, but in clinical practice, it is found that many patients think it is a toothache. In fact, there is a big difference between trigeminal neuralgia and toothache. After the trigeminal nerve emanates from the brainstem, it passes through the skull and innervates the muscles and skin sensations of the face. The first branch is in the eyes and forehead; the second branch is below the eye fissure and above the mouth and lips; and the third branch is in the jaw. Patients with trigeminal neuralgia encountered in clinical practice often present with pain in the third branch, which is the lower jaw. The paroxysmal pain that occurs in the lower jaw of trigeminal neuralgia lasts from a few seconds to a few minutes per attack, and the intervals are not painful at all and are completely normal; the pain is lightning-like, electric shock-like, electric shock, and severe pain during the attack; when washing the face, brushing the teeth, drinking, talking, or even blowing a little cold wind can induce a painful attack; thus, there is still a big difference between toothache and trigeminal neuralgia, and the former tends to have periodontitis, dental pulpitis, dental caries, etc. Often an experienced dentist, after examination and treatment, can completely distinguish between trigeminal neuralgia and toothache.