If the anterior descending stenosis is 40%, it is recommended to use antiplatelet aggregating drugs and lipid-lowering drugs to control the further development of stenosis. Most of the anterior descending branch stenosis 40% is due to coronary atherosclerosis, which is the basic pathological changes of coronary heart disease, at this time, it is recommended to use antiplatelet aggregation drugs such as aspirin, clopidogrel combined with lipid-lowering drugs such as atorvastatin, rasuvastatin and other medications, to control the stenosis further aggravation, to avoid leading to myocardial infarction and other situations. However, the drugs need to be used under the guidance of a doctor. At the same time, it is recommended to have a low-salt and low-fat diet, quit smoking and drinking, avoid staying up all night, and exercise appropriately. If symptoms such as chest tightness, chest pain, panic, shortness of breath, etc. occur, it is recommended to consult a regular hospital in a timely manner to avoid delaying the condition.