Osteolytic bone destruction refers to the complete loss of bone structure due to disease and its replacement by an abnormal structure or substance. Osteolytic bone destruction is usually caused by long-term chronic aseptic inflammation, abnormal bone metabolism, local infections, bone tumors and other osteolytic changes. Such cases need to be clearly diagnosed by CT, MRI, ECT and other relevant examinations, so as to determine the specific degree of bone destruction and find the primary focus. If it is caused by localized injury, the area of osteolysis is usually relatively small, and this condition usually improves gradually on its own. However, if it is caused by malignant tumors, the area of bone destruction is relatively large, and the specific treatment needs to be determined according to the specific pathological type of the malignant tumor. If the patient has osteolytic bone destruction phenomenon, it is recommended to go to the regular hospital for examination to cooperate with the doctor’s treatment.