Retrograde ejaculation is usually manifested by the absence of semen ejaculation or a very small and thin semen volume after normal erection or during masturbation to retrieve semen (the fluid is only prostatic fluid or urethral secretion, and there is no real sperm component), but at this time the collection of urine centrifugation can often obtain sperm, the ejaculatory excitement of such patients is normal, which can clinically lead to male infertility. Etiology: change in ejaculatory habits (this etiology is common in men of marriage age in the reproductive center and can be primary or occur when preparing for childbirth. It may be associated with excessive masturbation, fertility stress, and work stress.) ; history of pelvic surgery (surgery may cause damage to the nerves and blood vessels controlling ejaculation, resulting in the disappearance of normal forward ejaculation and its conversion to retrograde ejaculation.) History of chronic diseases (diabetes, neurological diseases and other systemic diseases can also lead to impairment of the normal ejaculatory mechanism and the inability to develop forward ejaculation.) (History of medication taking (taking certain psychotropic drugs can also lead to retrograde ejaculation); unknown cause. Diagnosis and treatment: Currently, diagnosis mostly relies on past medical history, history of medication use, and urinalysis of sperm. For treatment, medication is ineffective and aids such as biofeedback and psychological counseling can be tried, but often assisted reproduction techniques are still needed to obtain offspring. The main points of assisted reproduction treatment: artificial insemination or “in vitro fertilization” can be chosen according to the quality of urine sperm; while the female partner enters the ovulation cycle, the male partner needs to take sodium bicarbonate tablets to alkalize the urine to prepare for sperm extraction in the urine; male reproductive medicine consultation to avoid misdiagnosis or overtreatment.