Red dots on the neck in AIDS may be a manifestation of skin lesions in the acute infection or AIDS phase of the disease. Acute phase skin lesions are associated with damage to the immune system and HIV viremia, while skin lesions in the AIDS phase may be a manifestation of a comorbidity with other diseases. Skin lesions may be present in both the acute infection and AIDS phases of HIV and can manifest as red dots on the neck. In the acute HIV infection period, which is mainly 1-3 weeks after infection with the virus, the rash is mainly caused by acute damage to the immune system and HIV viremia, and usually subsides on its own within a month. During the AIDS period, due to the severe damage of the patient’s immune system, various diseases may be combined, and the symptoms of skin lesions may also be manifested as red dots on the neck, such as eczema, allergic purpura, and so on. When AIDS patients have red spots on their necks, it is recommended that they go to the hospital in time to improve the relevant examinations and clarify the specific causes.