Granuloma of the external auditory canal is mostly caused by local infection, and is considered to be related to local infection and disease. It is recommended to pay attention to the care of the affected area, as soon as possible to the hospital otorhinolaryngology department to follow the doctor’s instructions to apply the appropriate drugs, if necessary, through surgical treatment. 1. Local infection: the skin of the external auditory canal is relatively delicate, the local role of external forces, such as digging too much, resulting in damage to the external auditory canal, secondary infection and the formation of granuloma. When taking a bath or swimming, the external ear canal gets water, bacteria invade and form an infection, which then develops into a granuloma. It is recommended to pay attention to local care, avoid scratching, water, etc., if necessary, need to follow the doctor’s instructions for local or systemic application of antibiotics. In the early stage of the disease, topical medications such as ofloxacin ear drops, lomefloxacin hydrochloride ear drops and other anti-infective treatments are given to patients with a history of drug allergy. Hydrogen peroxide can be added if necessary. 2. Disease: purulent otitis media pus impregnation or systemic diseases, such as diabetes mellitus, endocrine disorders, granuloma of the external auditory canal may occur. It is recommended to go to the otorhinolaryngology department of the hospital as soon as possible, and follow the doctor’s instructions to treat it through drug control or surgical resection. Regular change of medication is needed, which can promote recovery, and active treatment of primary diseases is needed at the same time. In summary, in daily life, we need to keep the external auditory canal clean, dry, do not stimulate the local. Once granuloma appears in the external auditory canal, it is recommended to go to the ENT department of the hospital as soon as possible and follow the doctor’s instructions for treatment.