Mean hemoglobin concentration, or MCHC, refers to the concentration of hemoglobin per liter of red blood cells, and the normal range is 316~354 g/L. Elevated MCHC is rare, and high MCHC alone has no clinical significance, and needs to be combined with other indexes to make a comprehensive judgment. 1. Mean hemoglobin concentration, together with mean red blood cell volume and mean red blood cell hemoglobin content, is called the mean red blood cell index, which is helpful for the diagnosis and differential diagnosis of anemia. Low mean hemoglobin concentration can be seen in microcytic hypochromic anemia. 2. Anemias with normal mean hemoglobin concentration include normocytic anemia, simple microcytic anemia, and macrocytic anemia. 3. A single high mean hemoglobin concentration is usually of no clinical significance. When the average hemoglobin concentration is high, you should consult a doctor in time, complete the relevant examination, combine with other indicators to determine the cause, and receive treatment under the guidance of a physician to avoid delaying the condition.