Questions related to Gamma Knife related issues

Compared with surgery, the benefits of gamma knife

1, less restricted by blood vessels, because blood vessels have a higher tolerance to radiation, when the tumor infiltrates the blood vessels when surgery is difficult and the use of higher safety; Li Gong, Department of Oncology, Armed Forces General Hospital

2, not restricted by site, radiation is invisible, for those parts where surgical exposure is difficult or important functional area or tumor invasion cannot be removed, radiotherapy can be used, for early small lesions can also get the chance of radical treatment.

3.Non-invasive, low impact on the whole body, most patients with poor physical condition can also tolerate it.

4, can treat multiple lesions throughout the body, such as lung metastases of liver cancer, can be treated with radiotherapy for the primary foci in the liver at the same time, dealing with secondary lesions in the lungs.

What conditions can be met to do gamma knife?

1.The conditions that can do radical gamma knife treatment (effect: basic radical cure of liver cancer)

Good general physical condition.

A single lesion less than 5 cm in diameter.

or a large lesion and several small lesions on one lobe of the liver at the same time

the total volume of the lesion does not exceed 60% of the liver volume

absence of significant cancerous thrombi on imaging.

Basic normal liver function, cirrhosis is not obvious; no distant metastasis.

2, can do palliative gamma knife treatment conditions (effect: basic control of palliative disease)

intrahepatic lesions of 5 cm or more

or multiple lesions with a volume of more than 60% of the total volume of the liver

the presence of cancerous thrombi within the main trunk or left and right branches of the portal vein

the presence of obstructive jaundice in the tumor near the hilar region.

the presence of lung, bone or lymph node metastases or the presence of compression symptoms, regardless of whether the primary focus is controlled or not

Surgical or interventional treatment with residual, uncontrolled or intrahepatic spread of the cancer.

Which conditions are not suitable for Gamma Knife?

1, a large amount of ascites (ascites can be considered again after it is controlled).

2, with the presence of jaundice (can be reconsidered after the jaundice subsides or is significantly reduced).

3, abnormal liver function, such as elevated ALT, albumin below 35g/L, prolonged prothrombin time (can be reconsidered after normalization).

4, bleeding tendency; symptoms of upper gastrointestinal bleeding; obvious cirrhosis, hypersplenism, blood image below normal; very poor general condition, KPS score below 40; huge or extensive intrahepatic lesions with jaundice, ascites or multiple metastases; with hepatic coma, can not do gamma knife treatment.