High blood pressure and high low pressure require active antihypertensive treatment. The choice of drugs should be based on the first-line clinical antihypertensive drugs, such as diuretics, beta receptor antagonists, calcium channel blockers, angiotensin converting enzyme inhibitors, and angiotensin ll receptor antagonists. When choosing these antihypertensive drugs, it is necessary to select antihypertensive drugs that are suitable for patients according to their specific conditions, the effectiveness and tolerability of the drugs, and to individualize antihypertensive therapy. Long-acting agents should be selected and used in combination when necessary. It is also necessary to actively control other cardiovascular risk factors while lowering blood pressure, and to maintain a good lifestyle for a long time so that blood pressure can reach the standard for a long time, thus reducing the damage to the heart, brain and kidney target organs and preventing the comorbidities of hypertension.