Drinking alcohol the day before is not recommended for injections the next day because alcohol tends to cause nausea, vomiting, redness and itching of the skin, and some medications may also cause similar symptoms. It is easy to confuse the cause of the injection at such a time, so the injection is not recommended. However, if the injection is necessary due to an unexpected situation, it is necessary to make a judgment by considering whether the injection medication will react with alcohol. If the injection medication reacts with alcohol, the injection cannot be given, and if the injection medication does not react with alcohol, the injection can be given. Before the injection, you need to explain to the doctor the first day of drinking, so that the doctor can easily make a judgment. 1, can not be injected: If the injection medication and alcohol will react, such as cefmetazole, cefamandole, cefoperazone and other cephalosporins, metronidazole, ornidazole and other nitroimidazoles, then you can not be injected. Because cephalosporins and nitroimidazoles can occur with alcohol disulfiram-like reaction, manifested as facial and general skin flushing, excessive sweating, headache, dizziness, decreased blood pressure, panic, nausea, vomiting and other symptoms, serious cases may occur chest pain, respiratory distress, myocardial infarction, drowsiness, acute liver injury, and even shock and death; 2. Cases that can be injected: If there is no reaction between injection medication and alcohol, it is possible to injection, such as naloxone hydrochloride, can be injected intramuscularly to treat acute alcohol poisoning, and intramuscular injection of metoclopramide can relieve nausea, vomiting and other gastrointestinal symptoms after drinking. In addition, it takes about three days for the alcohol in the body to be metabolized completely, so if you drink alcohol the day before, try to avoid vaccination the next day to prevent the occurrence of situations where alcohol in the body causes aggravation of adverse reactions to the vaccine and reduces the effectiveness of the vaccine.