Amlodipine besylate and potassium chlorosartan can be used together. Amlodipine benzenesulfonate tablets belong to the calcium antagonist, potassium chlorosartan tablets belong to the angiotensin II receptor antagonist, can be used to treat hypertension, the two have different mechanisms of action, there are no contraindications and efficacy, can be used in combination, but need to be based on the specific condition of the patient’s physician. Amlodipine benzenesulfonate is contraindicated in people who are allergic to dihydropyridines or the components of the drug. Chlorosartan potassium tablets are contraindicated in people who are allergic to any components of the product, people with impaired liver or kidney function, women in the middle and late stages of pregnancy, and it is forbidden to use this product in combination with aliskiren-containing drugs. Amlodipine benzenesulfonate has adverse reactions such as nausea, abdominal pain, palpitations (rapid heartbeat, often accompanied by panic). Chlorosartan potassium has adverse reactions such as dizziness, low blood pressure, and liver and kidney impairment. Amlodipine benzenesulfonate may increase the risk of hypotension, worsening angina or myocardial infarction, and liver impairment. Chlorosartan potassium may have the potential for angioedema, liver and kidney damage. Both drugs need to be used under the guidance of a physician, and the joint use should be based on the patient’s specific condition.