There is no need to take aspirin when platelets drop to the normal range. Aspirin has the effect of inhibiting platelet aggregation, antipyretic and analgesic, anti-inflammatory and so on. For patients with high platelets to take aspirin, generally need platelets greater than 500 × 10^9 / L can be taken. It can effectively inhibit the function of platelets and reduce their ability to aggregate, as a way to avoid the formation of blood clots. Because aspirin has the effect of anti-platelet aggregation, bleeding tendency can occur after the reduction of platelets, such as nosebleed, tooth bleeding, skin purpura, etc. Therefore, the platelet count down to the normal range can no longer use aspirin. It is better to take the medicine for a fixed period of time, not to miss the dose, but also should be regularly drawn blood to check the platelet value in the blood routine, and then decide whether to take aspirin or not. The use of medication should be regulated under the guidance of a doctor.