There is no obvious pain or slight pain after the removal of simple teeth, but for wisdom teeth, especially the buried wisdom teeth, which are more invasive and take longer to remove, pain after extraction is a very normal postoperative physiological phenomenon, and the patient will have a gradual pain reduction process within 3 days after extraction. At this stage, you can apply symptomatic antipyretic and analgesic drugs for pain, such as aspirin, ibuprofen and acetaminophen, which are the first-stage antipyretic and analgesic drugs for pain, and have relatively good analgesic effect with little side effects. For physiological pain after wisdom tooth removal, the application of opioid drugs is not suitable. If the pain is not physiological, but suddenly appears more than 3 days after wisdom tooth extraction, or if there is redness, swelling and pus in the extraction wound, or if there is a bad taste in the mouth, it is necessary to be alerted to the possibility of not only physiological pain after wisdom tooth extraction, but also post-operative infection of the extraction wound. It is necessary to perform incision and drainage for the extraction wound and to apply anti-inflammatory drugs to control systemic infection in addition to pain relief drugs for the whole body.