A high level of epididymal protein 4 in women suggests the presence of malignant tumors, but as much as possible, it should be combined with the tumor marker CA125 for a detailed determination, because when there are potentially benign tumors, there will also be such an increase, and a pelvic CT scan should be performed to determine if there are any abnormalities. There may be more causes, such as ovarian cysts and fibroids in the pelvis, breast tumors and abnormal thyroid function, thyroid tumors, and nodules in the lungs, all of which have a tendency to be high. As far as possible, MRI should be done for detailed judgment to determine what the specific nature is, because the final result can only be judged based on pathological analysis. High human epididymal protein 4 does not necessarily mean that there is a tumor, but only has a certain reference basis.