The causes of soreness in the thigh muscles above the knee are different, and the treatment methods are also different, as follows: a. Overexertion, such as participation in long-distance running or other physical exercise, may cause the body anaerobic enzymatic production of lactic acid, lactic acid accumulation in the thigh muscles appear thigh soreness symptoms, the treatment has the following several methods. 1, pay attention to rest, avoid strenuous sports, avoid overexertion, can be carried out on the legs The appropriate massage to promote the contraction of the leg muscles, which will help the metabolism of lactic acid decomposition, you can also apply heat to the leg, can promote local blood circulation, relieve muscle pain; 2, oral anti-inflammatory painkillers, such as ibuprofen or diclofenac sodium and other drugs, can relieve muscle pain, you can also use safflower oil or topical anti-inflammatory painkillers, such as Furtalin ointment, these can relieve the symptoms of muscle swelling. Second, if long-term muscle soreness, may also be suffering from varicose veins in the lower limbs, or lumbar disc herniation, need to go to the hospital for further examination to clarify the diagnosis, and according to the cause of targeted treatment.