Side effects of tobramycin eye drops vary from person to person, usually they cause more local irritation such as eyelid swelling and conjunctival erythema, but in case of allergic reactions such as rash and difficulty in breathing, they can be life-threatening and the medication must be stopped immediately. Side effects such as conjunctival erythema, swelling or burning sensation of the eyelids, rash, itchy skin, and difficulty in breathing may be experienced after using tobramycin eye drops. The drug is an aminoglycoside that enters the bacteria and binds to the 30s subunit of the bacterial ribosome, causing inhibition of bacterial protein synthesis, thus acting as an antimicrobial agent, and can be used to treat localized infections of the external eye and its appendages caused by sensitive bacteria. Please note that this drug and other aminoglycosides are contraindicated in people who are allergic to this drug and other aminoglycosides. Use with caution in the following conditions: water loss; hearing or vestibular hypofunction; abnormal renal or hepatic function; myasthenia gravis or Parkinson’s disease. It should also be used with caution in children, elderly patients and pregnant women. Breastfeeding should be discontinued when used by nursing mothers. The drug is cross-allergic with streptomycin, gentamicin and other aminoglycoside antibiotics and has potential nephrotoxicity and ototoxicity, so it should not be combined with other nephrotoxicity or ototoxicity of the drug, and with furosemide, etanercept and other diuretics, plasma substitutes such as dextran, and other drugs, which will also increase its nephrotoxicity and ototoxicity. If you need to use the drug patients, please under the guidance of the doctor strictly follow the instructions of the doctor to take medication, do not self-medication.