Patients with synovial hyperplasia can be treated with medication and surgery as follows: First, medication: mild synovial hyperplasia only requires reducing joint weight bearing, avoiding joint trauma and exposure to cold, while taking oral celecoxib and loxoprofen sodium to enhance joint stability, which can bring relief to mild synovial hyperplasia. Second, surgical treatment: Severe synovial hyperplasia can produce joint pain, limited joint movement and joint effusion, which requires consideration of surgical treatment, such as minimally invasive joint surgery and arthroscopic removal of inflammatory hyperplastic synovium, which can improve clinical symptoms. If the patient is an elderly patient with deformity of the joint, artificial joint replacement surgery should be considered to remove the synovial hyperplasia while correcting the force line of the limb and restoring the normal function of the joint, and the patient’s normal life and work can be ensured. Patients need to cooperate with functional exercises after surgery, such as muscle strength and intensity training, so as to enhance the stability of the joint and protect the synovial membrane.