The constant leakage of urine from the catheter may be related to the catheter itself, or it may be caused by cystinosis factors. 1. Catheter factors: If the catheter, drainage bag is broken, or the connection is not tight, the catheter belt switch is not closed in time, can cause urine leakage phenomenon. If the catheter is left in place for a long period of time, folding or obstruction of the catheter can also cause leakage. When urine leakage occurs, the first step should be to check the catheter and drainage bag for abnormalities, and it is recommended that the catheter and drainage tube be replaced regularly. 2. Bladder factors: If the leakage occurs between the urethra and the urethral orifice, it is considered to be caused by bladder spasm, as the catheter will cause irritation to the bladder mucosa, so that the forced urethral muscle over-contracted, the bladder pressure increases, and urine leakage from the catheter to the surrounding. It is also accompanied by symptoms such as urinary urgency and frequency, which can be controlled by taking anti-bladder spasm medications such as tolterodine under the guidance of a doctor. Therefore, it is important to keep a close eye on any abnormalities when leaving a catheter in place.