The inexplicable crying of a five year old child falling asleep at night may be caused by physiological factors, calcium deficiency, gastrointestinal pathology and other factors. Different causes, different treatment methods, including general treatment as well as drug treatment. 1. Physiological factors: such as nightmares, suffered excessive shock, can lead to inexplicable crying at night, parents should be more soothing to the child, to communicate with the child, so that the child to eliminate psychological barriers, usually can be improved on their own. 2. Calcium deficiency: when the calcium deficiency is too much, it may lead to children’s leg cramps at night, causing painful symptoms, which will cause children to cry more than, after diagnosis should follow the doctor’s advice to supplement vitamin D and more sun exposure, which will help calcium supplementation. 3. gastrointestinal lesions: such as indigestion, can cause abdominal pain, abdominal distension, may make the child cry at night symptoms, can use probiotics and other drugs to regulate gastrointestinal function, such as bacillus subtilis bacillus granules and so on, and to light diet. The five-year-old child fell asleep at night inexplicably crying need to consult a doctor in a timely manner to clarify the diagnosis, in accordance with the doctor’s instructions for targeted treatment, to avoid delaying the treatment time. All of the above drugs should be used under the guidance of a doctor.