Simultaneous low white blood cells, platelets, and red blood cells below 2 may be hypoproliferative leukemia, commonly seen in acute myeloid leukemia. Low white blood cells, platelets, red blood cells, and decreased whole blood cells are mainly seen in hypoproliferative leukemia. The disease has an insidious onset and progresses more slowly, and the affected population is mostly elderly, with anemia symptoms such as fatigue, palpitations, shortness of breath, and pallor being more common. Bleeding may be manifested as petechiae and ecchymoses on the skin. Leukemia cell infiltration is not obvious, and liver and spleen enlargement are uncommon. Due to low hematopoietic function and immunity, there is a risk of serious infections, and patients are mostly unable to tolerate stronger chemotherapy, which requires timely transfusion of red blood cells and platelets to support treatment. Specific diagnosis and treatment should be carried out under the guidance of physicians.