From the eugenic point of view, patients with primary epilepsy should be prohibited from marriage and childbirth, but there are no clear rules in China, the following points for reference. (1) Marriage of close relatives should be prohibited, especially marriage and childbirth of close relatives who are both patients with primary epilepsy. (2) Marriage of non-related patients with primary epilepsy should be discouraged, especially if one or both have a family history of epilepsy, and birth should be prohibited if they are already married. (3) If one or both parents of a patient with epilepsy have epilepsy and the patient has had a child with epilepsy, the birth of a second child should be prohibited. (4) Patients with generalized grand mal seizure type epilepsy who have extensive spike and slow complex waves or multifocal spike EEG manifestations, and who have similar EEG abnormalities in their siblings, may marry normal people, but should be prohibited from having children. Epilepsy is mostly seen in adolescents, and once they reach the age of marriage, whether they can get married and have children is a great concern for patients and their relatives. The concerns are threefold: ① Will epilepsy be inherited to the next generation? (2) Does pregnancy have any effect on epilepsy? ③Will taking epilepsy drugs affect the fetus? First, epilepsy has an irregular genetic impact in a few cases and has little impact on most. The size of the impact is mainly related to the cause of the disease. The incidence of patients is 3-4% in relatives of primary patients and 0-1% in secondary patients, indicating that the primary effect is high and the closer the blood relationship the higher the incidence. The prevalence of epilepsy in the third generation is 20% when both parents have epilepsy or have a child with epilepsy, therefore, primary patients can marry but should be restricted from having children. The more distant the family history, the better. Second, 45% of people with epilepsy have an increased number of seizures after pregnancy, especially when taking western drugs, which are metabolized through the liver, fetal tissue and placenta are susceptible to reduced serum concentrations of antiepileptic drugs, which cannot control seizures, and if the dose is increased, it has an effect on both the mother and fetus. Thirdly, the incidence of fetal teratogenicity is 2.2%-13.8%, especially for western anti-epileptic drugs. Cleft palate, cleft lip, and cardiac anomalies are common. The incidence of teratogenicity is related to the mother’s age, family history, and medical history (such as diabetes) on the one hand, and to the drugs used, especially some western drugs, on the other. In order to prevent fetal teratogenesis, it is better to take herbal medicine, and the symptoms should be controlled for more than 3 years, and the age should not exceed 35 years. Patients or those who have deformed genetic disease in their family should not have children, and patients who have miscarried, stillbirth or produced abnormal babies should be extra careful in re-birth.