Swelling and pain at the root of the tongue is considered to be related to pathological factors such as tongue contour papillitis, tongue root ulcers, stomatitis, pharyngolaryngitis and tongue tumors. 1. Tongue contour papillitis: when the tongue contour papillae are inflamed, the inflammation can stimulate the local area causing the contour papillae to bulge and swell, which can be manifested as swelling and pain at the root of the tongue. 2. Ulcers at the root of the tongue: Ulcers at the root of the tongue are mostly related to dental bite injuries, bad dietary habits such as eating too fast, which can cause localized ulcers at the root of the tongue with symptoms of swelling and pain. 3. Stomatitis: oral inflammation caused by bacterial or viral infection can stimulate the root of the tongue causing localized swelling, pain and other symptoms. 4. Pharyngolaryngitis: Inflammation of pharyngeal mucosa caused by bacteria and viruses can cause dryness, pain, itchiness, difficulty in swallowing, etc. Inflammation can also stimulate the root of the tongue to produce localized symptoms of swelling and pain. 5. Tumor of tongue: it may be related to smoking, consuming too hot food for a long time and other bad habits, when there is a tumor at the root of tongue, it may cause local swelling and pain at the root of tongue. If the swelling and pain at the root of the tongue is not relieved or even aggravated for a long time, one should go to the hospital in time to find out the cause and treat the cause actively to avoid delaying the condition.